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Weight Loss & Wellness / Acne Prescription Treatments

Clearer Skin, Customized to Your Needs

Board-Certified Clinicians

Prescribed by licensed providers

Custom-Compounded Rx

Formulas built for your skin

Delivered to Your Door

Shipped directly from the pharmacy

If you've ever felt:

You've tried every drugstore cleanser, spot treatment, and serum — and nothing makes a real dent.

Breakouts keep cycling, leaving behind dark marks, texture, or scarring.

You need prescription-strength ingredients but dread the waitlist and expense of a dermatologist.

Skin Clique connects you with a licensed provider who prescribes a custom formula for your acne — active ingredients combined into a single nightly cream designed for your skin.

What Prescription Acne Care Can Do

Your provider builds a formula around your skin — not a mass-market bottle.

Active Breakouts

Tretinoin, azelaic acid, clindamycin, and other prescription actives target active acne at the root.

Post-Acne Marks

Fade the red and dark marks left behind by breakouts with ingredients like tranexamic acid and hydroquinone.

Cystic & Hormonal Acne

For deeper, cyclical breakouts, your provider can prescribe oral medications alongside topical therapy.

Clogged Pores & Congestion

Custom retinoid strength to clear congestion without the irritation of over-the-counter trial-and-error.

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PRESCRIPTION OPTIONS

Treatments built around your acne.

Custom-compounded topicals and targeted orals — all $79/month with provider access and home delivery.

Radiance Cream

Starting at $79/mo

Radiance Cream

Topical

Azelaic acid, clindamycin phosphate, niacinamide, tranexamic acid, tretinoin, dexpanthenol, and BHT — targets breakouts, calms inflammation, and fades post-acne marks.

Clarity Cream

Starting at $79/mo

Clarity Cream

Topical

Azelaic acid, clindamycin phosphate, niacinamide, tranexamic acid, and zinc pyrithione — formulated for inflammatory acne with whiteheads.

Unblemished Cream

Starting at $79/mo

Unblemished Cream

Topical

Azelaic acid, clindamycin phosphate, and zinc pyrithione — built for hormonal acne along the jawline.

Spironolactone

Starting at $79/mo

Spironolactone

Oral

Oral medication that targets hormonal acne by controlling oil production and soothing irritation.

Doxycycline

Starting at $79/mo

Doxycycline

Oral

Oral antibiotic that reduces acne-causing bacteria and addresses inflammatory acne.

FIND A PROVIDER NEAR YOU

Ready to see the difference?

Get Started with Acne Prescription Treatments.

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  1. 1

    Book a Virtual or In-Person Consult

    Your licensed provider reviews your skin, medical history, and goals — in person or via secure telehealth.

  2. 2

    Custom Rx Is Prescribed

    Your provider designs a formula from ingredients like tretinoin, azelaic acid, clindamycin, niacinamide, and more.

  3. 3

    Delivered + Adjusted

    Your prescription arrives at your door. Your provider follows up to adjust strength and ingredients based on how your skin responds.

Is Acne Prescription Treatments right for you?

Who is a good candidate for Acne Prescription Treatments?

  • Teens and adults with comedonal, inflammatory, hormonal, or cystic acne that hasn't responded to OTC products
  • Anyone who's cycled through benzoyl peroxide, salicylic acid, or adapalene without sustained improvement
  • Patients whose acne leaves post-inflammatory hyperpigmentation (dark spots) or scars — prescription treatment addresses both
  • Those interested in a combination approach: prescription topicals plus periodic in-office chemical peels

Who should avoid acne prescription treatments?

  • Pregnant or breastfeeding individuals — tretinoin and several other prescription actives are contraindicated; your provider can discuss safe alternatives
  • Patients looking for an immediate overnight fix — prescription skincare works over weeks, not days, and some patients experience initial purging
  • Anyone unwilling to commit to daily SPF use alongside prescription treatment (tretinoin increases photosensitivity)

Acne Rx FAQs

Prescription-strength actives (like tretinoin) aren't available over the counter — and we combine them with complementary ingredients into a single formula calibrated to your skin.

Most patients see noticeable improvement in 8–12 weeks. Acne gets worse before it gets better for some — your provider will set expectations.

Yes. For hormonal or cystic acne, your provider may prescribe oral antibiotics, spironolactone, or refer you for isotretinoin where appropriate.

Your prescription refills on a schedule that works for you. You can pause, adjust, or cancel anytime.

No — tretinoin and most retinoids are Category X and should be discontinued before conception. If you're pregnant or planning to become pregnant, tell your provider so they can adjust your formula to pregnancy-safe alternatives.

Yes — this is called purging. As retinoids accelerate cell turnover, existing congestion surfaces faster. This typically resolves within 4–6 weeks. It's distinct from a true allergic reaction; your provider can help you tell the difference.

Yes. Hormonal acne — typically appearing along the jawline and chin, worsening around your cycle — responds well to spironolactone (an oral medication) combined with topical prescription treatment. Your provider will assess your pattern and recommend the appropriate combination.