What Is Radiesse? The Filler That Also Stimulates Collagen

What Is Radiesse?

Radiesse is an FDA-approved dermal filler made of calcium hydroxylapatite (CaHA) microspheres suspended in a water-based gel carrier. Unlike hyaluronic acid fillers, Radiesse works through a two-phase mechanism: it provides immediate volumization and then stimulates the body's own collagen production over time.

How Is Radiesse Different from Hyaluronic Acid Fillers?

What Is Radiesse Used For?

Radiesse excels at:
- Volume restoration — cheeks, chin, and jawline
- Hand rejuvenation — FDA-approved for this indication; reduces the appearance of visible tendons and bones
- Facial contouring — jaw definition, chin projection
- Deeper folds — nasolabial folds, marionette lines

Radiesse is not appropriate for the lips or certain delicate areas where softer, reversible fillers are preferred.

How Long Does It Last?

Radiesse typically lasts 12–18 months or longer, making it one of the longer-lasting filler options available. The CaHA microspheres gradually absorb and are replaced by your own collagen, leaving natural-looking, lasting results.

Is Radiesse Safe?

Radiesse has been used safely for over 20 years and has an extensive safety record. It is biocompatible and eventually fully absorbed by the body. The most common side effects are temporary bruising, swelling, and redness at the injection site.

Important: Radiesse cannot be dissolved with hyaluronidase if a revision is needed—this is a key consideration in treatment planning. An experienced provider will discuss this during your consultation.

Skin Clique providers are trained in advanced filler techniques and will help you determine whether Radiesse is the right tool for your goals.